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Although it is almost impossible to say what causes pancreatic cancer in a particular person, there are several basic principles of biology that can help us understand how pancreatic cancer develops.
Basic biological principles
Pancreatic cancer is a disease caused by DNA damage. This damage is known to biologists as a mutation. Mutations can be genetically inherited from one parent or acquired over many years. The first case inevitably depends on the fact that diploid organisms acquire two copies of each chromosome. The second case may depend on a certain type of behavior, such as smoking, which introduces carcinogens (cancer-causing chemicals) into the body, as well as coincidences - errors in the delicate mechanism of DNA copying.
Ductal adenocarcinoma of the pancreas
Some forms of pancreatic cancer are more serious than others. This is, for example, ductal adenocarcinoma. It is clear that mutations are at the heart of this type of clinical condition. However, the more difficult question is what exactly causes the mutation. As already mentioned, the reasons may be different. However, in the case of ductal adenocarcinoma, progress has already been made in identifying the relevant molecular mechanisms.
Pancreatic cancer depends on a certain protein
Under the guidance of scientists from the Cold Spring Harbor Laboratory, an experiment was conducted that showed that pancreatic cancer cells are "dependent" on a key protein. In the language of biology, proteins that help express genetic information in every cell of the body are called transcription factors. The analysis showed that during the development of aggressive cancer, a gene called Tumor-Protein 63 (or TP63) was present, a protein that usually does not belong to the pancreas.
Instead, this protein's job is to participate in the creation of specialized skin cells known as squamous cells. The study showed that in the case of ductal adenocarcinoma, the protein transformed pancreatic cells into something they shouldn't be doing. The good news is that cancer cells are so dependent on this protein that suppressing it would be an important marker in the treatment of this condition. Profitez au maximum de votre expérience de pari avec le code promo 1xbet nouveaux joueurs sont accueillis avec un bonus de bienvenue généreux pouvant atteindre 130 000 XOF. Cette somme impressionnante vous offre un départ fantastique pour explorer l'énorme sélection de events sportifs et de jeux de casino disponibles sur la plateforme.Vous bénéficiez d'un bonus de bienvenue de 100% sur votre premier dépôt, pour une valeur pouvant atteindre 130 000 XOF. De quoi explorer en détail. Grâce à lui, votre premier dépôt est intégralement doublé, pour un maximum de 130 000 XOF. Une aubaine pour tout de jeux en ligne.
Basic biological principles
Pancreatic cancer is a disease caused by DNA damage. This damage is known to biologists as a mutation. Mutations can be genetically inherited from one parent or acquired over many years. The first case inevitably depends on the fact that diploid organisms acquire two copies of each chromosome. The second case may depend on a certain type of behavior, such as smoking, which introduces carcinogens (cancer-causing chemicals) into the body, as well as coincidences - errors in the delicate mechanism of DNA copying.
Ductal adenocarcinoma of the pancreas
Some forms of pancreatic cancer are more serious than others. This is, for example, ductal adenocarcinoma. It is clear that mutations are at the heart of this type of clinical condition. However, the more difficult question is what exactly causes the mutation. As already mentioned, the reasons may be different. However, in the case of ductal adenocarcinoma, progress has already been made in identifying the relevant molecular mechanisms.
Pancreatic cancer depends on a certain protein
Under the guidance of scientists from the Cold Spring Harbor Laboratory, an experiment was conducted that showed that pancreatic cancer cells are "dependent" on a key protein. In the language of biology, proteins that help express genetic information in every cell of the body are called transcription factors. The analysis showed that during the development of aggressive cancer, a gene called Tumor-Protein 63 (or TP63) was present, a protein that usually does not belong to the pancreas.
Instead, this protein's job is to participate in the creation of specialized skin cells known as squamous cells. The study showed that in the case of ductal adenocarcinoma, the protein transformed pancreatic cells into something they shouldn't be doing. The good news is that cancer cells are so dependent on this protein that suppressing it would be an important marker in the treatment of this condition. Profitez au maximum de votre expérience de pari avec le code promo 1xbet nouveaux joueurs sont accueillis avec un bonus de bienvenue généreux pouvant atteindre 130 000 XOF. Cette somme impressionnante vous offre un départ fantastique pour explorer l'énorme sélection de events sportifs et de jeux de casino disponibles sur la plateforme.Vous bénéficiez d'un bonus de bienvenue de 100% sur votre premier dépôt, pour une valeur pouvant atteindre 130 000 XOF. De quoi explorer en détail. Grâce à lui, votre premier dépôt est intégralement doublé, pour un maximum de 130 000 XOF. Une aubaine pour tout de jeux en ligne.